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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFDH
All Species:
36.06
Human Site:
T47
Identified Species:
56.67
UniProt:
Q16134
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16134
NP_004444.2
617
68495
T47
P
R
I
T
T
H
Y
T
I
Y
P
R
D
K
D
Chimpanzee
Pan troglodytes
XP_517508
617
68419
T47
P
R
I
T
T
H
Y
T
I
Y
P
R
D
K
D
Rhesus Macaque
Macaca mulatta
XP_001097120
616
68420
T47
P
R
I
T
T
H
Y
T
I
Y
P
R
D
K
D
Dog
Lupus familis
XP_853781
600
66768
T47
P
R
I
T
T
H
Y
T
I
Y
P
R
D
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q921G7
616
68072
T46
P
Q
I
T
T
H
Y
T
V
H
P
R
E
K
D
Rat
Rattus norvegicus
Q6UPE1
616
68180
T46
P
Q
I
T
T
H
Y
T
I
H
P
R
E
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510390
669
74482
T99
P
R
I
T
T
H
Y
T
I
H
P
R
D
K
D
Chicken
Gallus gallus
NP_001026705
477
53116
Frog
Xenopus laevis
NP_001087869
616
68418
T46
P
R
I
T
T
H
Y
T
I
Y
P
R
G
Q
D
Zebra Danio
Brachydanio rerio
NP_001004598
617
68912
T47
P
R
I
T
T
H
Y
T
V
Y
P
R
D
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610536
604
65970
W46
P
R
E
K
D
E
R
W
T
E
V
D
M
E
R
Honey Bee
Apis mellifera
XP_624722
606
67014
W46
P
R
E
L
D
Q
R
W
K
D
V
N
M
E
R
Nematode Worm
Caenorhab. elegans
Q11190
597
65317
E47
K
D
V
D
L
A
R
E
S
D
V
Y
D
V
V
Sea Urchin
Strong. purpuratus
XP_792035
613
67384
R47
I
P
R
E
T
D
D
R
W
K
D
V
E
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08822
631
69615
L54
T
E
E
E
K
E
L
L
N
E
P
R
A
R
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
92.2
N.A.
92.3
93.1
N.A.
82
65.4
84.2
80.8
N.A.
65.1
67.7
59.9
70
Protein Similarity:
100
99.6
99
94.6
N.A.
95.7
95.9
N.A.
88.4
70.6
91.9
90.5
N.A.
78.9
80.8
75.6
81.8
P-Site Identity:
100
100
100
100
N.A.
73.3
80
N.A.
93.3
0
86.6
93.3
N.A.
13.3
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
0
93.3
100
N.A.
20
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
14
7
7
0
0
14
7
7
47
0
67
% D
% Glu:
0
7
20
14
0
14
0
7
0
14
0
0
20
14
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
60
0
0
0
20
0
0
0
0
0
% H
% Ile:
7
0
60
0
0
0
0
0
47
0
0
0
0
0
0
% I
% Lys:
7
0
0
7
7
0
0
0
7
7
0
0
0
54
0
% K
% Leu:
0
0
0
7
7
0
7
7
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
14
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% N
% Pro:
74
7
0
0
0
0
0
0
0
0
67
0
0
0
0
% P
% Gln:
0
14
0
0
0
7
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
60
7
0
0
0
20
7
0
0
0
67
0
7
14
% R
% Ser:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% S
% Thr:
7
0
0
60
67
0
0
60
7
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
14
0
20
7
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
14
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
60
0
0
40
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _